Dr. Martin Hirst

January 2005

Job title and General Description
Research Associate – Genome Sciences Centre

I lead the Gene Expression group at the Genome Sciences Centre. Our group is focused on understanding the complex interplay of genes in normal and disease states. One aspect of this is our work with the Mammalian Gene Collection (MGC) program whose mandate is to create a publicly accessible resource of fully-sequenced single-gene clones for complete genomes, including human, mouse, and rat – the latter two offering important models for cancer research. We are also involved in generating digital gene expression profiles through the construction of SAGE libraries to identify and rescue genes involved in development, stem cell renewal and disease progression.

What specific skills and qualities are needed to do your job?
A job in science research requires a keen interest in science and love of discovery. You need to find excitement in learning and have the dedication to pursue a question to its conclusion. The management aspects of my job require good ‘people skills’. You need to be able to but together a good team of people and keep them motivated and interested in the project they are working on.

What do you like most about your work?
I feel very fortunate to have a job that contributes to humanity. I enjoy those amazing moments when the reasons of why a biological system has developed a mechanism to deal with a problem become clear. I also enjoy interacting with the people that I work with.

What don’t you like about your job?
There are no major things that I don’t like about my job. There are little things with every job that might be a bother but I can just let those things go.

Where do you see your career going from here?
My goal is to obtain a position that would allow me to design a research program and obtain funding to support it. At the BC Cancer Agency this is a Scientist or Primary Investigator position.

What is the range in salary that comes with your job?
The salary range for a research associate position can vary from around $50,000 – $80,000.

When did you know you wanted to work in sciences?
I was originally planning to become a chemical engineer. When I was at UBC I became interested in genetics and molecular biology.

What is your educational background?
At UBC I did a BSc in Honours Biochemistry and Molecular Biology. I also did my PhD at UBC in yeast genetics studying transcriptional regulation. After obtaining my PhD I was involved in the start up of a biotech company called Interomex Biopharmaceuticals. I worked at this position for four years before starting at the BCCA Genome Sciences Centre.

What were your favorite courses?
I really enjoyed my 3rd year genetics course and my 4th year honours lab course at UBC.

What other hobbies and interests do you have?
I have a cabin on Sonora Island that I love spending time at with my friends and family . I am involved in many outdoors activities including, fishing, skiing and the occasional triathlons. I also enjoy reading 19th and 20th century Russian literature.

Do you have any advice for young people thinking about getting into your line of work?
Computer skills are essential in today’s workforce. An in depth knowledge of databases and higher level computer systems is very important for working in the field of genomics.

Remember, there are many angles to take in the field of genomics. The service industry that supplies the genomics industry also has many career opportunities.

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