Dr. Angela Devlin

May 2005

Job title and General Description
Assistant Professor of Pediatrics at UBC
Research Scientist in the Nutrition Research Program at BCRI

My job includes working in the laboratory and teaching at the graduate level in metabolism and disease. I am mainly involved in research. I started my lab in BC’s Children’s Hospital October 2004. As a research scientist I am responsible for many things including, developing the research approach, writing grant proposals and papers, setting up the lab and training staff. I am also involved in some hands-on laboratory work.

I study ways in which genomics and nutrition impact our health. Proteomics and metabolism are included in the scope of my research. My main focus is on epigenetic factors that impact gene regulation and metabolism. This includes mechanisms such as DNA methylation patterns that can change and impact gene expression. One condition that I study is hyperhomocysteinemia, which is due to elevated levels of the amino acid homocysteine. This condition can lead to cardiovascular problems. Diet has an impact on epigenetic factors that impact gene expression and subsequent levels of homocysteine in our system. We study animal models that demonstrate changes in this metabolic process due to changes in methylation and diet.

What specific skills and qualities are needed to do your job?
Communication skills are essential in my work environment. I need to have excellent written and spoken communication skills. Explaining and promoting my ideas and research plans is critical. When working on research it is very important to be very diligent in following the planned course of action without getting discouraged when things don’t go exactly as expected. You need to be able to stick with it and carry on.

What do you like most about your work?
My job allows me to be creative and innovative. My field is relatively new and there are a lot of exciting areas to explore. I also enjoy working with my new staff and students.

What don’t you like about your job?
As with most research, there is always the uncertainty of funding. I need to be continuously applying for funding from various sources. This can be frustrating.

Where do you see your career going from here?
At the moment I am the head of my lab and setting up my own research projects. I would like to continue to grow with this and work on my own research program.

What is the range in salary that comes with your job?
As an assistant professor, the salary ranges from $50-70,000. It does vary depending on the school and department involved.

When did you know you wanted to work in sciences?

In high school I became interested in working in science. I had a good memory and did well in my science classes.

What is your educational background? Degrees? Specific courses?
I did my B.Sc. in Human Nutrition at the University of Western Ontario. Then I came to Vancouver and did my Ph.D. at UBC in the Interdisciplinary Graduate Program including nutrition, molecular biology and biochemistry. I continued my studies at UC Davis where I did a Post Doc in the Department of Internal Medicine, looking at Genetics and Nutrition. I studied polymorphic gene variations and their impact on gene function. I did another Post Doc in Iowa where I studied vascular biology.

What was your favorite course(s) and why?
Some of the courses that I enjoyed the most include Metabolic Biochemistry and Genetics, Biochemistry and Disease, and Inborn Errors of Metabolism.

What other hobbies and interests do you have?
My three year old daughter keeps me very busy and I love spending time with her. We enjoy doing a lot of outdoor activities.

Do you have any advice for young people thinking about getting into your line of work?
Try different options. Don’t give up on things…. be diligent and stick with it. Let things evolve and adapt with the change. Don’t be ridged.
If you think working in the laboratory would be a good career for you, try it out in your undergrad. Find out if it suites you. Look into doing a co-op program to get the hands on experience.

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